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1884611-28-2

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1884611-28-2 Structure

1884611-28-2 Structure
IdentificationBack Directory
[Name]

Anti-aging agent 1
[CAS]

1884611-28-2
[Synonyms]

Anti-aging agent 1
Hazard InformationBack Directory
[Uses]

Anti-aging agent 1 (compound 24) is a derivative of piperlongumine (HY-N2329) (PL). Anti-aging agent 1 exhibits a 50-fold enhancement in senolytic activity against senescent WI-38 fibroblasts compared to PL[1].
[References]

[1] Xuan Zhang, et al. Design and optimization of piperlongumine analogs as potent senolytics. Bioorg Med Chem Lett. 2023. DOI:10.1016/j.bmcl.2023.129593
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