| Identification | Back Directory | [Name]
1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE | [CAS]
18851-33-7 | [Synonyms]
1,10-PHENANTHROLINE HYDROCHLORIDE
1,10-PhenanthrolineHydrochlorideGr
1,10-PHENANTHROLINE CHLORIDE MONOHYDRATE
1,10-Phenanthroline hydrochloride hydrate
1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE
O-PHENANTHROLINE HYDROCHLORIDE MONOHYDRATE
1,10-Phenanthroline hydrochloride, GR 99%+
o-Phenanthroline monohydrate hydrochloride
1,10-PHENANTHROLINE HYDROCHLORIDE MONOHYDRATE
1,10-Phenanthroline monohydrate hydrochloride
1,10-PHENANTHROLINE HYDROCHLORIDE MONOHYDRATE AR
1,10-Phenanthroline hydrochloride hydrate (1:1:1)
1,10-PHENANTHROLINE HYDROCHLORIDE MONOHYDRATE (O-)
1,10-Phenanthroline Hydrochloride Monohydrate,>98%
1,10-Phenanthroline monohydrate monohydrochloride
1,10-Phenanthroline monohydrochloride monohydrate 97%
1,10-Phenanthroline hydrochloride monohydrate >=99.0% (AT)
1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE ISO 9001：2015 REACH
1,10-Phenanthroline Hydrochloride Monohydrate extrapure AR, 99.5%
1,10-Phenanthroline monohydrate hydrochloride, o-Phenanthroline monohydrate hydrochloride
1,10-Phenanthroline chloride monohydrate GR for analysis and redox indicator [reagent for iron(II)] Reag. Ph Eur | [EINECS(EC#)]
627-064-8 | [Molecular Formula]
C12H11ClN2O | [MDL Number]
MFCD00150061 | [MOL File]
18851-33-7.mol | [Molecular Weight]
234.68 |
| Chemical Properties | Back Directory | [Melting point ]
224-225 °C(lit.)
| [bulk density]
370kg/m3 | [storage temp. ]
Store below +30°C. | [solubility ]
H2O: 0.1 g/mL, clear
| [form ]
Solid | [color ]
Colorless crystals | [Water Solubility ]
Soluble in water. | [BRN ]
4007967 | [Stability:]
Stable for 2 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months. | [InChI]
1S/C12H8N2.ClH.H2O/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;;/h1-8H;1H;1H2 | [InChIKey]
NDLHUHRGAIHALB-UHFFFAOYSA-N | [SMILES]
O.Cl.c1cnc2c(c1)ccc3cccnc23 |
| Safety Data | Back Directory | [Hazard Codes ]
T,N | [Risk Statements ]
25-50/53 | [Safety Statements ]
45-60-61 | [RIDADR ]
UN 2811 6.1/PG 3
| [WGK Germany ]
3
| [F ]
8 | [TSCA ]
Yes | [HS Code ]
2933 99 80 | [HazardClass ]
6.1 | [PackingGroup ]
III | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 1 | [Toxicity]
LD50 orally in Rabbit: 132 mg/kg |
| Hazard Information | Back Directory | [Description]
1,10-Phenanthroline (18851-33-7) is a high affinity chelator of divalent metal ions and may be used to inhibit zinc metalloenzymes.1? It is a potent inhibitor of JAMM-type isopeptidases (DUBs) acting via chelation of an active site Zn2+.? It may be used when preparing cell lysates for enrichment of ubiquitinated proteins? which are especially sensitive to DUBs in the JAMM family.2,3 | [Chemical Properties]
White fine crystalline powder | [Uses]
1,10-Phenanthroline monohydrochloride monohydrate is used as an analytical reagent for colorimetric determination of iron. | [References]
1) Swann?et al?(1981)?Zinc metalloenzyme properties of active and latent collagenase from rabbit bone;. Biochem.J.,?195?41
2) Cooper?et al. (2009) K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1; EMBO J.,?28?621
3) Lu?et al. (2015)?Substrate degradation by the proteasome: A single-molecule kinetic analysis; Science,?348?200 |
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J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
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Alfa Aesar
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http://chemicals.thermofisher.cn |
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Energy Chemical
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www.energy-chemical.com |
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Sigma-Aldrich
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Shanghai Uchem Inc.
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