| Identification | Back Directory | [Name]
Cl-4AS-1 | [CAS]
188589-66-4 | [Synonyms]
Cl-4AS-1
(4aα,4bβ,6aα,7α,9aβ,9bα,11aβ)-N-(2-Chlorophenyl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1,4,6a-trimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide | [Molecular Formula]
C26H33ClN2O2 | [MDL Number]
MFCD31689240 | [MOL File]
188589-66-4.mol | [Molecular Weight]
441.01 |
| Chemical Properties | Back Directory | [Boiling point ]
631.1±55.0 °C(Predicted) | [density ]
1.206±0.06 g/cm3(Predicted) | [storage temp. ]
Store at RT | [solubility ]
Soluble to 10 mM in DMSO and to 10 mM in ethanol | [form ]
Powder | [pka]
13.70±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Cl-4AS-1 is an inhibitor of 5α-Reductase 1 and 5α-Reductase 2. | [in vivo]
Cl-4AS-1 produces no significant reduction in prostate weight in intact animals and in castrates rats caused a significant increase of ventral prostate weight[1]. | Animal Model: | ORX rats[1] | | Dosage: | 10 mg/kg | | Administration: | I.s.; 7 days | | Result: | Effect of Cl-4AS-1 on prostate and seminal vesicle growth.
|
| [storage]
Store at RT |
|
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|