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Ecdysoside B (compound 6b) is a pregnanoside compound isolated from the plant Ecdysanthera rosea. Ecdysoside B and its derivatives and isomers shows anticancer, immunosuppressive and anti-inflammatory activities. Ecdysoside B shows cytotoxicity to a variety of human tumor cell lines, including PANC-1 (human pancreatic cancer cells), A375 (human melanoma cells) and U87 (brain glioma U87 cells). Ecdysoside B can be used for research in the areas of cancer, immunomodulation and anti-inflammato[1]. | [References]
[1] Zhang Z, et al. Merging total synthesis and NMR technology for deciphering the realistic structure of natural 2, 6-dideoxyglycosides[J]. Science Advances, 2024, 10(15): eadn1305. DOI:10.1126/sciadv.adn1305 |
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