| Identification | Back Directory | [Name]
2-{7-FLUORO-2-OXO-4-[2-(4-THIENO[3,2-C]PYRIDIN-4-YLPIPERAZIN-1-YL)ETHYL]QUINOLIN-1(2H)-YL}ACETAMIDE | [CAS]
189003-92-7 | [Synonyms]
SL 650472
Trelanserin
2-[7-fluoro-2-oxo-4-[2-(4-thieno[3,2-c]pyridin-4-ylpiperazin-1-yl)ethyl]quinolin-1-yl]acetamide
1(2H)-QuinolineacetaMide,7-fluoro-2-oxo-4-[2-(4-thieno[3,2-c]pyridin-4-yl-1-piperazinyl)ethyl]-
2-{7-FLUORO-2-OXO-4-[2-(4-THIENO[3,2-C]PYRIDIN-4-YLPIPERAZIN-1-YL)ETHYL]QUINOLIN-1(2H)-YL}ACETAMIDE | [Molecular Formula]
C24H24FN5O2S | [MDL Number]
MFCD03792903 | [MOL File]
189003-92-7.mol | [Molecular Weight]
465.54 |
| Hazard Information | Back Directory | [Uses]
Trelanserin (SL-650472) is a 5-HT receptor antagonist and also an effective in vitro smooth muscle contraction antagonist, competing against the contractions induced by sumatriptan (HY-B0121B) with a pA2 of 8.17±0.36[1]. | [References]
[1] A M Galzin, et al. Effects of SL 65.0472, a novel 5-HT receptor antagonist, on 5-HT receptor mediated vascular contraction. Eur J Pharmacol. 2000 Sep 22;404(3):361-8. DOI:10.1016/s0014-2999(00)00630-0 |
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