| Identification | Back Directory | [Name]
Ozagrel sodium | [CAS]
189224-26-8 | [Synonyms]
Xanbo
D01684
Ozapen
KCT-0809
Athrombone
Ozagrel Na
Ozapen (tn)
OZAGREL SODIUM
Ozagrel Impurity 45
Ozagrel sodium (jan)
Ozagrel sodium USP/EP/BP
(130952-46-4) ozagrel sodium
OZAGREL SODIUM (OKY-046 SODIUM)
sodium (E)-3-(4-((1H-imidazol-1-yl)methyl)phenyl)acrylate
(E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]acrylic acid sodium salt
(2E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]-2-propenoic acid sodium salt
2-Propenoic acid,3-[4-(1H-imidazol-1-ylmethyl)phenyl]-, sodium salt (1:1), (2E)- | [EINECS(EC#)]
1806241-263-5 | [Molecular Formula]
C13H11N2NaO2 | [MOL File]
189224-26-8.mol | [Molecular Weight]
250.23 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [form ]
Solid | [color ]
White to off-white | [Water Solubility ]
Water: ≥ 44 mg/mL (175.84 mM) | [InChI]
InChI=1S/C13H12N2O2.Na/c16-13(17)6-5-11-1-3-12(4-2-11)9-15-8-7-14-10-15;/h1-8,10H,9H2,(H,16,17);/q;+1/p-1/b6-5+; | [InChIKey]
NCNYJCOBUTXCBR-IPZCTEOASA-M | [SMILES]
[Na+].C([O-])(=O)/C=C/C1=CC=C(CN2C=NC=C2)C=C1 |
| Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
Ozagrel sodium (OKY-046 sodium) is a thromboxane A2 (TXA2) synthase inhibitor. Ozagrel sodium is an antiplatelet agent, which selectively inhibits human platelet aggregation with an IC50 of 53.12 μM[1]. | [IC 50]
TXA2 | [References]
[1] Max Seidy Saito, et al. Antiplatelet pyrazolopyridines derivatives: pharmacological, biochemical and toxicological characterization. J Enzyme Inhib Med Chem. 2016 Dec;31(6):1591-601. DOI:10.3109/14756366.2016.1158712 |
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