| Identification | Back Directory | [Name]
BOC-12-ADO-OH | [CAS]
18934-81-1 | [Synonyms]
BOC-12-ADO-OH
BOC-NH-(CH2)11-COOH
BOC-12-AMINOLAURIC ACID
BOC-12-AMINODODECANOIC ACID
Boc-12-Ado-OH >=98.0% (TLC)
N-Boc-12-aminododecanoic acid
12-(BOC-AMINO)DODECANOIC ACID
T-BUTOXYCARBONYL-12-AMINOLAURIC ACID
T-BUTOXYCARBONYL-12-AMINODODECANOIC ACID
N-T-BUTYLOXYCARBONYL-12-AMINO-DODECANOIC ACID
N-tert-Butoxycarbonyl-12-aminododecanoic acid
N-TERT-BUTYLOXYCARBONYL-12-AMINO-DODECANOIC ACID
12-{[(tert-butoxy)carbonyl]amino}dodecanoic acid
12-[(2-methylpropan-2-yl)oxycarbonylamino]dodecanoic acid
Dodecanoic acid, 12-[[(1,1-dimethylethoxy)carbonyl]amino]- | [Molecular Formula]
C17H33NO4 | [MDL Number]
MFCD00235887 | [MOL File]
18934-81-1.mol | [Molecular Weight]
315.45 |
| Chemical Properties | Back Directory | [Melting point ]
83.5-84.5 °C | [Boiling point ]
454.5±18.0 °C(Predicted) | [density ]
0.997±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [form ]
powder | [pka]
4.78±0.10(Predicted) | [color ]
colorless to white | [BRN ]
1980302 | [Major Application]
peptide synthesis | [InChI]
InChI=1S/C17H33NO4/c1-17(2,3)22-16(21)18-14-12-10-8-6-4-5-7-9-11-13-15(19)20/h4-14H2,1-3H3,(H,18,21)(H,19,20) | [InChIKey]
NNPOZNVKUHYVEJ-UHFFFAOYSA-N | [SMILES]
C(O)(=O)CCCCCCCCCCCNC(OC(C)(C)C)=O |
| Hazard Information | Back Directory | [Description]
Boc-12-Ado-OH can be used as a PROTAC linker in the synthesis of PROTACs. Boc-12-Ado-OH is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine. | [Uses]
Boc-12-Ado-OH can be used as a PROTAC linker in the synthesis of PROTACs. Boc-12-Ado-OH is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine. | [reaction suitability]
reaction type: Boc solid-phase peptide synthesis |
|
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Shanghai GL Peptide Ltd.
|
| Telephone: |
+86-21-61263310 13764994101 |
| Website: |
www.chemicalbook.com/supplier/10480342/ |
| Company Name: |
Nextpeptide Inc
|
| Telephone: |
+86-0571-81612335 +8613336028439 |
| Website: |
http://www.nextpeptide.com/ |
| Company Name: |
Binhai gill polypeptide co. LTD
|
| Telephone: |
021-61263389 13524856427 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList326362/0_EN.htm |
|