| Identification | Back Directory | [Name]
AC-LEU-GLU-VAL-ASP-PNA | [CAS]
189684-49-9 | [Synonyms]
AC-LEVD-PNA
AC-LEU-GLU-VAL-ASP-PNA
CASPASE-4 SUBSTRATE (AFC)
CASPASE-4 SUBSTRATE (CHROMOGENIC)
AC-LEU-GLU-VAL-ASP-PARANITROANILIDE
CASPASE 4 (ICH-2) SUBSTRATE 1, CHROMOGENIC | [Molecular Formula]
C28H40N6O11 | [MDL Number]
MFCD01631265 | [MOL File]
189684-49-9.mol | [Molecular Weight]
636.65 |
| Chemical Properties | Back Directory | [Boiling point ]
1086.614±65.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.327±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
4.035±0.10(predicted) | [color ]
White to off-white | [Sequence]
Ac-Leu-Glu-Val-Asp-{pNA} |
| Hazard Information | Back Directory | [Uses]
Ac-LEVD-pNA is a chromogenic substrate for caspase-4 and can be used to detect caspase-4 activity[1]. | [References]
[1] Arduíno DM, et al. Endoplasmic reticulum and mitochondria interplay mediates apoptotic cell death: relevance to Parkinson's disease. Neurochem Int. 2009 Sep;55(5):341-8. DOI:10.1016/j.neuint.2009.04.004 |
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