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189696-20-6

189696-20-6 Structure

189696-20-6 Structure
IdentificationBack Directory
[Name]

MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH
[CAS]

189696-20-6
[Synonyms]

MCA-DEVDAPK (DNP)
MCA-DEVDAPK(DNP)-OH
CASPASE-3 SUBSTRATE (MCA)
CPP32 Fluorogenic Substrate III
CASPASE-3 SUBSTRATE III, FLUOROGENIC
MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)
MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH
7-methoxycoumarin-4-acetyl-asp-glu-*val-asp-ala-P
MCA-DEVDAPK(DNP)-OH;CPP32 FLUOROGENIC SUBSTRATE III
7-METHOXYCOUMARIN-4-ACETYL-ASP-GLU-*VAL- ASP-ALA-PRO
MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS: DNP[MCA-DEVDAP-K: DNP]
7-METHOXYCOUMARIN-4-ACETYL-ASP-GLU-VAL-ASP-ALA-PRO-(2,4-DINITROPHENYL)-LYS
L-Lysine,N-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-α-aspartyl-L-α-glutamyl-L-valyl-L-α-aspartyl-L-alanyl-L-prolyl-N6-(2,4-dinitrophenyl)-
L-Lysine, N-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-α-aspartyl-L-α-glutamyl-L-valyl-L-α-aspartyl-L-alanyl-L-prolyl-N6-(2,4-dinitrophenyl)- (9CI)
[Molecular Formula]

C50H62N10O22
[MDL Number]

MFCD00798785
[MOL File]

189696-20-6.mol
[Molecular Weight]

1155.08
Chemical PropertiesBack Directory
[Boiling point ]

1561.2±65.0 °C(Predicted)
[density ]

1.455±0.06 g/cm3(Predicted)
[storage temp. ]

−20°C
[solubility ]

Formic Acid: 1 mg/ml
[form ]

Lyophilized powder
[pka]

3.67±0.21(Predicted)
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Description]

Mca-DEVDAPK(Dnp)-OH is a fluorogenic substrate for caspase-3. It is cleaved by caspase-3 to release the fluorescent moiety 7-methoxycoumarin-4-acetyl (Mca), which can be used to quantify caspase-3 activity.

[Uses]

Mca-DEVDAP-K(Dnp)-OH is a fluorogenic substrate for caspase-3[1].
[IC 50]

Caspase-3
[References]

[1] Fertig Georg. Method for the detection of the apoptosis activated cysteine protease Caspase 3 by specific antibody-binding and fluorescence enzyme assay. EP0955377A1
[Sequene]

Mca-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-OH
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