| Identification | Back Directory | [Name]
PDE1-IN-2 | [CAS]
1904611-63-7 | [Synonyms]
PDE1-IN-2
PDE1 inhibitor 2
PDE1IN2,PDE1 IN 2,PDE-1-IN-2 | [Molecular Formula]
C16H21BrN4O2 | [MDL Number]
MFCD30738016 | [MOL File]
1904611-63-7.mol | [Molecular Weight]
381.27 |
| Chemical Properties | Back Directory | [Boiling point ]
563.8±60.0 °C(Predicted) | [density ]
1.70±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 25 mg/mL (65.57 mM) | [form ]
Solid | [pka]
-0.33±0.40(Predicted) | [color ]
White to gray |
| Hazard Information | Back Directory | [Description]
PDE1-IN-2 is an inhibitor of PDE1 extracted from patent WO2016/55618 A1, example 31; has IC50 values of 6, 140 and 164 nM for PDE1C, PDE1B and PDE1A, respectvely. | [Uses]
PDE1-IN-2 is a PDE1 inhibitor extracted from patent WO2016/55618 A1, example 31. PDE1-IN-2 has IC50 values of 6 nM, 140 nM and 164 nM for PDE1C, PDE1B and PDE1A, respectvely. PDE1-IN-2 is developed for the research of neurodegenerative disorders and psychiatric disorders[1]. | [IC 50]
PDE1A: 164 nM (IC50); PDE1B: 140 nM (IC50); PDE1C: 6 nM (IC50) | [References]
[1]. WO2016055618A1 |
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