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19056-75-8

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19056-75-8 Structure

19056-75-8 Structure
IdentificationBack Directory
[Name]

5-Hydroxy-2′,3,4′,7-tetramethoxyflavone
[CAS]

19056-75-8
[Synonyms]

5-Hydroxy-2′,3,4′,7-tetramethoxyflavone
2-(2,4-dimethoxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-chromen-4-one
[Molecular Formula]

C19H18O7
[MOL File]

19056-75-8.mol
[Molecular Weight]

358.34
Chemical PropertiesBack Directory
[Melting point ]

132-133 °C
[Boiling point ]

587.4±50.0 °C(Predicted)
[density ]

1.36±0.1 g/cm3(Predicted)
[pka]

6.14±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

BCRP/ABCG2-IN-1 is the inhibitor of breast cancer resistance protein (BCRP/ABCG2), with IC50 of 5.98 μM, that can be used in multidrug resistance of breast cancer[1].
[References]

[1] Kapil Juvale, et al. Synthesis and biological evaluation of flavones and benzoflavones as inhibitors of BCRP/ABCG2. Eur J Med Chem. 2013 Sep:67:115-26. DOI:10.1016/j.ejmech.2013.06.035
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