| Identification | Back Directory | [Name]
Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)- | [CAS]
190728-24-6 | [Synonyms]
Cabozantinib Nitro Analog
Cabozantinib Genotoxic Impurity II
6,7-dimethoxy-4-(4-nitrophenoxy)-Quinoline
Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)-
6,7-dimethoxy-4-(4-nitrophenoxy)quinolineQ: What is
6,7-dimethoxy-4-(4-nitrophenoxy)quinoline Q: What is the CAS Number of
6,7-dimethoxy-4-(4-nitrophenoxy)quinoline | [Molecular Formula]
C17H14N2O5 | [MDL Number]
MFCD22581649 | [MOL File]
190728-24-6.mol | [Molecular Weight]
326.3 |
| Chemical Properties | Back Directory | [Boiling point ]
480.9±40.0 °C(Predicted) | [density ]
1.319±0.06 g/cm3(Predicted) | [pka]
4.33±0.30(Predicted) | [InChI]
InChI=1S/C17H14N2O5/c1-22-16-9-13-14(10-17(16)23-2)18-8-7-15(13)24-12-5-3-11(4-6-12)19(20)21/h3-10H,1-2H3 | [InChIKey]
YRYKZXCOGVCXBN-UHFFFAOYSA-N | [SMILES]
N1C2C(=CC(OC)=C(OC)C=2)C(OC2=CC=C([N+]([O-])=O)C=C2)=CC=1 |
| Hazard Information | Back Directory | [Uses]
6,7-Dimethoxy-4-(4-nitrophenoxy)quinoline is a related compound of cabozantinib (CAS# 849217-68-1) with potential anticancer activity. It can be used in the preparation of nicotinamide derivatives as Aurora kinase inhibitors, nquinolinyloxyphenylbenzenesulfonamides as AXL kinase inhibitors, N-phenyl-N'-{4-(4-quinolyloxy)phenyl}ureas as vascular endothelial growth factor receptor 2 (VEGFR-2) tyrosine kinase inhibitors, and phenoxyquinolines as specific inhibitors of platelet-derived growth factor receptor tyrosine kinase. |
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