| Identification | Back Directory | [Name]
BMS-986195 | [CAS]
1912445-55-6 | [Synonyms]
CPD1640
BMS-986195
BMS-986195 USP/EP/BP
Branebrutinib (BMS-986195)
BMS-986195; BMS986195; BMS986195
(S)-4-(3-(but-2-ynamido)piperidin-1-yl)-5-fluoro-2,3-dimethyl-1H-indole-7-carboxamide
1H-Indole-7-carboxamide, 5-fluoro-2,3-dimethyl-4-[(3S)-3-[(1-oxo-2-butyn-1-yl)amino]-1-piperidinyl]- | [Molecular Formula]
C20H23FN4O2 | [MDL Number]
MFCD31631584 | [MOL File]
1912445-55-6.mol | [Molecular Weight]
370.42 |
| Questions And Answer | Back Directory | [Uses]
Branebrutinib (BMS-986195) is a potent inhibitor of BTK with IC50 values of 0.1 nM, 0.9 nM, 1.5 nM, 5 nM for BTK, TEC, BMX, TXK, respectively. |
| Chemical Properties | Back Directory | [density ]
1.32±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:87.0(Max Conc. mg/mL);234.86(Max Conc. mM)
Ethanol:38.0(Max Conc. mg/mL);102.58(Max Conc. mM) | [form ]
A crystalline solid | [pka]
11.91±0.20(Predicted) | [color ]
White to off-white |
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