ChemicalBook--->CAS DataBase List--->1914987-47-5

1914987-47-5

1914987-47-5 Structure

1914987-47-5 Structure
IdentificationBack Directory
[Name]

H-GLU(EDANS)-PRO-LEU-PHE-ALA-GLU-ARG-LYS(DABCYL)-OH
[CAS]

1914987-47-5
[Synonyms]

H-GLU(EDANS)-PRO-LEU-PHE-ALA-GLU-ARG-LYS(DABCYL)-OH
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[5-(2-aminoethylamino)naphthalen-1-yl]sulfonylamino]-4-carboxybutanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]propanoyl]amino]-4-carboxybutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-6-[[4-[[4-(dimethylamino)phenyl]diazenyl]benzoyl]amino]hexanoic acid
[Molecular Formula]

C72H97N17O16S
[MDL Number]

MFCD08702758
[MOL File]

1914987-47-5.mol
[Molecular Weight]

1488.71
Chemical PropertiesBack Directory
[density ]

1.40±0.1 g/cm3(Predicted)
[pka]

-0.26±0.40(Predicted)
[Sequence]

{Glu(EDANS)}-Pro-Leu-Phe-Ala-Glu-Arg-{Lys(DABCYL)}
Hazard InformationBack Directory
[Uses]

Glu(EDANS)-Pro-Leu-Phe-Ala-Glu-Arg-Lys(DABCYL) is a calpain substrate. The excitation wavelength is 380 nm and the emission wavelength is 500 nm for Glu(Edans)-Pro-Leu-Phe-Ala-Glu-Arg-Lys(Dabcyl)[1].
[References]

[1] Jo H, et al. Development of α-helical calpain probes by mimicking a natural protein-protein interaction. J Am Chem Soc. 2012 Oct 24;134(42):17704-13. DOI:10.1021/ja307599z
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