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191545-24-1

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191545-24-1 Structure

191545-24-1 Structure
IdentificationBack Directory
[Name]

Epieriocalyxin A
[CAS]

191545-24-1
[Synonyms]

Epieriocalyxin A
Spiro[1H-7,9a-methanocyclohepta[c]pyran-4(3H),1'-[3]cyclohexene]-6'-carboxaldehyde, 4a,5,6,7,8,9-hexahydro-5',5',8-trimethyl-1,2',9-trioxo-, (1'S,4aS,6'R,7R,8R,9aS)-
[Molecular Formula]

C20H24O5
[MDL Number]

MFCD20260394
[MOL File]

191545-24-1.mol
[Molecular Weight]

344.4
Hazard InformationBack Directory
[Uses]

epi-Eriocalyxin A (Epieriocalyxin A), a diterpenoid isolated from Isodon eriocalyx, induces colon cancer apoptosis. epi-Eriocalyxin A also inhibits ERK1/2 and JNK activation, which suppresses Bcl-2 expression[1].
[References]

[1] Zhou Wang, et al. Epieriocalyxin A Induces Cell Apoptosis Through JNK and ERK1/2 Signaling Pathways in Colon Cancer Cells. Cell Biochem Biophys. 2015 Nov;73(2):559-564. DOI:10.1007/s12013-015-0687-4
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