| Identification | Back Directory | [Name]
Tenacissoside G | [CAS]
191729-43-8 | [Synonyms]
nacissoside G
Tenacissoside G
Tenacissimoside A
Pregnan-20-one, 12-(acetyloxy)-3-[[2,6-dideoxy-4-O-(6-deoxy-3-O-methyl-β-D-allopyranosyl)-3-O-methyl-β-D-arabino-hexopyranosyl]oxy]-8,14-epoxy-11-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]-, (3β,5α,11α,12β,14β,17α)-
(3beta,5alpha,11alpha,12beta,14beta,17alpha)-12-(Acetyloxy)-3-[[2,6-dideoxy-4-O-(6-deoxy-3-O-methyl-beta-D-allopyranosyl)-3-O-methyl-beta-D-arabino-hexopyranosyl]oxy]-8,14-epoxy-11-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]pregnan-20-one | [Molecular Formula]
C42H64O14 | [MDL Number]
MFCD22417326 | [MOL File]
191729-43-8.mol | [Molecular Weight]
792.96 |
| Hazard Information | Back Directory | [Chemical Properties]
Soluble in methanol, ethanol, DMSO and other organic solvents, derived from customs clearance vine. | [Uses]
Tenacissoside G is a C21 steroid from the stems of Marsdenia tenacissima. Tenacissoside G reverses multidrug resistance in P-glycoprotein (Pgp)-overexpressing multidrug-resistant cancer cells[1][2]. | [Biological Activity]
Tenacissoside G is a C21 steroid derived from the stem of Marsdenia tenacissima. It reverses multidrug resistance in P-glycoprotein (Pgp)-overexpressing multidrug-resistant cancer cells. | [References]
[1] Lei YS, et al. [C21 steroids from the stems of Marsdenia tenacissima]. Yao Xue Xue Bao. 2008 May;43(5):509-12. PMID:18717339
[2] Hu YJ, et al. Tenacigenin B derivatives reverse P-glycoprotein-mediated multidrug resistance inHepG2/Dox cells. J Nat Prod. 2008 Jun;71(6):1049-51. DOI:10.1021/np070458f |
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| Company Name: |
WG reagent
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| Telephone: |
13391486464 |
| Website: |
www.wgchemical.com |
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