| Identification | Back Directory | [Name]
DDX3-IN-1 | [CAS]
1919828-83-3 | [Synonyms]
DDX3-IN-1
DDX3-IN-16d
DDX3 inhibitor 1
Urea, N-(2-methylphenyl)-N'-[4-(4-methyl-1H-1,2,3-triazol-1-yl)phenyl]- | [Molecular Formula]
C17H17N5O | [MDL Number]
MFCD32174274 | [MOL File]
1919828-83-3.mol | [Molecular Weight]
307.35 |
| Chemical Properties | Back Directory | [density ]
1.24±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 125 mg/mL (406.70 mM); Water: < 0.1 mg/mL (insoluble) | [form ]
Solid | [pka]
13.83±0.70(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
DDX3-IN-1 (Compound 16f) is a DEAD-box polypeptide 3 (DDX3) inhibitor with CC50s of 50 and 36 μM for HIV and HCV, respectively. Antiviral activity[1]. | [References]
[1] Brai A, et al. Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents. Proc Natl Acad Sci U S A. 2016 May 10;113(19):5388-93. DOI:10.1073/pnas.1522987113 |
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