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1922-48-1

1922-48-1 Structure

1922-48-1 Structure
IdentificationBack Directory
[Name]

16BETA-METHYL-16ALPHA,17ALPHA-EPOXYPREGNENOLONE
[CAS]

1922-48-1
[Synonyms]

Ambiguanol
16|-Methyl-16|,17|-epoxypregnenolone
16b-methyl-16a,17a-epoxypregnenolone
16,17-Epoxy-6-methylpregn-5-en-3-ol-20-one
16BETA-METHYL-16ALPHA,17ALPHA-EPOXYPREGNENOLONE
5-Pregnen-16α,17α-epoxy-16β-methyl-3β-ol-20-one
16,17-Epoxy-3-hydroxy-16-methyl-pregn-5-en-20-one
3β-Hydroxy-16β-methyl-16α,17α-oxido-Δ5-pregnenon-20
3β-Hydroxy-16β-methyl-16α,17α-epoxy-5-pregnen-20-one
(17R)-16β,17-Epoxy-3β-hydroxy-16-methylpregn-5-en-20-one
Pregn-5-en-20-one,16,17-epoxy-3-hydroxy-16-methyl-, (3b,16a)-
5-PREGNEN-16ALPHA,17ALPHA-EPOXY-16BETA-METHYL-3BETA-OL-20-ONE
3BETA-HYDROXY-16BETA-METHYL-16ALPHA,17ALPHA-EPOXY-5-PREGNEN-20-ONE
16-alpha,17-alpha-epoxy-3-beta-hydroxy-16-beta-methylpregn-5-en-20-one
5-Pregnen-16α,17α-epoxy-16β-methyl-3β-ol-20-one, 3β-Hydroxy-16β-methyl-16α,17α-epoxy-5-pregnen-20-one
[EINECS(EC#)]

217-651-3
[Molecular Formula]

C22H32O3
[MDL Number]

MFCD00022308
[MOL File]

1922-48-1.mol
[Molecular Weight]

344.49
Chemical PropertiesBack Directory
[Melting point ]

189-191 °C(Solv: acetone (67-64-1); hexane (110-54-3))
[Boiling point ]

462.3±45.0 °C(Predicted)
[density ]

1.17±0.1 g/cm3(Predicted)
[pka]

14.99±0.70(Predicted)
Safety DataBack Directory
[WGK Germany ]

3
Raw materials And Preparation ProductsBack Directory
Hazard InformationBack Directory
[Chemical Properties]

Crystalline compound, mp 165-185°C.
[Uses]

Used as Intermediate of dexamethasone acetate.
[Synthesis]

16beta-Methyl-16alpha,17alpha-epoxypregnenolone is prepared by reacting 3β-hydroxypregnant-5,16-dien-20-one-3-acetate with nitrosomethylurea.
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