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1923268-81-8

1923268-81-8 Structure

1923268-81-8 Structure
IdentificationBack Directory
[Name]

1,?2,?4,?5-?Tetrazine-?3-?butanoic acid, 6-?methyl-
[CAS]

1923268-81-8
[Synonyms]

(Me)Tz-butanoic acid
1,2,4,5-Tetrazine-3-butanoic acid, 6-methyl-
4-(6-methyl-1,2,4,5-tetrazin-3-yl)butanoic acid
[Molecular Formula]

C7H10N4O2
[MDL Number]

MFCD31560768
[MOL File]

1923268-81-8.mol
[Molecular Weight]

182.18
Chemical PropertiesBack Directory
[Boiling point ]

454.1±47.0 °C(Predicted)
[density ]

1.310±0.06 g/cm3(Predicted)
[pka]

4.43±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

(Me)Tz-butanoic acid is a click chemistry reagent containing an azide. (Me)Tz-butanoic acid is tetrazine linker for conjugation via Diels-Alder-reaction, i.e. copper-free Click reaction with dienophiles[1]. (Me)Tz-butanoic acid is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
[References]

[1] Sadowsky Jack Avid, et al. METHODS AND COMPOSITIONS FOR TIME DELAYED BIO-ORTHOGONAL RELEASE OF CYTOTOXIC AGENTS. WO2022197877. 2022
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