| Identification | Back Directory | [Name]
CYS-GLY | [CAS]
19246-18-5 | [Synonyms]
CYS-GLY Cys-Gly-OH L-Cys-Gly-OH H-CYS-GLY-OH cysteinylglycine CYS-GLY USP/EP/BP N-Cysteinylglycine L-CYSTEINYL GLYCINE glycine,n-cysteinyl n-l-cysteinyl-glycin Cys-Gly, ≥85% (HPLC) N-L-Cysteinylglycine Glycine, L-cysteinyl- Glutathione EP Impurity A L-Cysteinylglycine (~85%) L-CYSTEINYLGLYCINE MONOHYDRATE (R)-2-(2-aMino-3-MercaptopropanaMido)acetic acid 2-(2-amino-3-sulfanyl-propanoyl)aminoacetic acid Glutathione Impurity 12(Glutathione EP Impurity A) | [Molecular Formula]
C5H10N2O3S | [MDL Number]
MFCD00055567 | [MOL File]
19246-18-5.mol | [Molecular Weight]
178.21 |
| Chemical Properties | Back Directory | [Melting point ]
158 - 160oC | [Boiling point ]
459.0±45.0 °C(Predicted) | [density ]
1.373±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMSO (Slightly), Methanol (Slightly), Water (Slightly) | [form ]
Solid | [pka]
3.02±0.10(Predicted) | [color ]
White to Off-White | [Stability:]
Air Sensitive | [InChI]
1S/C5H10N2O3S/c6-3(2-11)5(10)7-1-4(8)9/h3,11H,1-2,6H2,(H,7,10)(H,8,9) | [InChIKey]
ZUKPVRWZDMRIEO-UHFFFAOYSA-N | [SMILES]
NC(CS)C(=O)NCC(O)=O |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
22-36 | [Safety Statements ]
26 | [WGK Germany ]
3
| [RTECS ]
MB9285800
| [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral Eye Irrit. 2 |
| Hazard Information | Back Directory | [Uses]
Cys-Gly has been used for derivatization by p-hydroxymercury benzoate (PHMB) for calibration of reversed phase chromatography coupled on-line and sequentially with a UV?visible diode array detector (RPLC-DAD). | [Definition]
ChEBI: A dipeptide consisting of glycine having an L-cysteinyl attached to its alpha-amino group. It is an intermediate metabolite in glutathione metabolism. | [General Description]
Cys-Gly, a dipeptide is a catabolic byproduct of glutathione. | [Biochem/physiol Actions]
Cys-Gly is a precursor for glutathione biosynthesis in the neurons. It favors reactive oxygen species generation in the presence of transition metal ions. A normal level of cys-gly is essential for normal cellular function. | [IC 50]
Human Endogenous Metabolite |
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