| Identification | Back Directory | [Name]
(D-SER4)-GOSERELIN | [CAS]
1926163-39-4 | [Synonyms]
(D-SER4)-GOSERELIN
(D-SER4,D-SER(TBU)6,AZAGLY10)-LHRH
Goserelin Impurity 1 （Goserelin EP Impurity A)
PYR-HIS-TRP-D-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZAGLY-NH2
(D-SER4,D-SER(TBU)6,AZAGLY10)-GONADOTROPIN-RELEASING HORMONE
(D-SER4,D-SER(TBU)6,AZAGLY10)-LUTEINIZING HORMONE-RELEASING FACTOR
(D-SER4,D-SER(TBU)6,AZAGLY10)-LUTEINIZING HORMONE-RELEASING HORMONE
(D-SER4)-GOSERELIN ; PYR-HIS-TRP-D-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZAGLY-NH2 | [Molecular Formula]
C59H84N18O14 | [MDL Number]
MFCD05663469 | [MOL File]
1926163-39-4.mol | [Molecular Weight]
1269.41 |
| Chemical Properties | Back Directory | [density ]
1.50±0.1 g/cm3(Predicted) | [storage temp. ]
-15°C | [pka]
9.82±0.15(Predicted) | [Sequence]
{Pyr}-His-Trp-{d-Ser}-Tyr-{d-Ser(tBu)}-Leu-Arg-Pro-{Azagly}-NH2 |
| Hazard Information | Back Directory | [Uses]
(D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH)[1]. | [References]
[1] Horvath JE, et al. Effects of long-term treatment with the luteinizing hormone-releasing hormone (LHRH) agonist Decapeptyl and the LHRH antagonist Cetrorelix on the levels of pituitary LHRH receptors and their mRNA expression in rats. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15048-53. DOI:10.1073/pnas.232579499 |
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