| Chemical Properties | Back Directory | [Boiling point ]
900.1±65.0 °C(Predicted) | [density ]
1.272±0.06 g/cm3(Predicted) | [pka]
13.40±0.46(Predicted) | [Sequence]
Ac-Gly-Ala-{Lys-AMC} |
| Hazard Information | Back Directory | [Uses]
Ac-GAK-AMC is a fluorescent substrate that can be used to measure protease activity. AMC (7-amino-4-methylcoumarin) is a fluorescent group. In the presence of protease, the protease will hydrolyze Ac-GAK-AMC into a fluorescent product[1]. | [References]
[1] Brian E Schultz, et al. Kinetics and comparative reactivity of human class I and class IIb histone deacetylases. Biochemistry. 2004 Aug 31;43(34):11083-91. DOI:10.1021/bi0494471 |
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