| Identification | Back Directory | [Name]
CDC801 | [CAS]
192819-27-5 | [Synonyms]
CDC801
3-(3-cyclopentyloxy-4-methoxyphenyl)-3-(1,3-dioxoisoindol-2-yl)propanamide
2H-Isoindole-2-propanamide, β-[3-(cyclopentyloxy)-4-methoxyphenyl]-1,3-dihydro-1,3-dioxo- | [Molecular Formula]
C23H24N2O5 | [MDL Number]
MFCD31544387 | [MOL File]
192819-27-5.mol | [Molecular Weight]
408.45 |
| Chemical Properties | Back Directory | [Melting point ]
165-166 °C | [Boiling point ]
639.7±55.0 °C(Predicted) | [density ]
1.325±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
16.06±0.40(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
CDC801 is a potent and orally active phosphodiesterase 4 (PDE4) and tumor necrosis factor-α (TNF-α) inhibitor with IC50 of 1.1 μM and 2.5 μM, respectively. | [IC 50]
PDE4 | [References]
[1] Man HW, et al. Discovery of (S)-N-[2-[1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl] acetamide (apremilast), a potent and orally active phosphodiesterase 4and tumor necrosis factor-alpha inhibitor. J Med Chem. 2009 Mar 26;52(6):1522-4. DOI:10.1021/jm900210d |
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https://www.bocsci.com |
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cjbscvictory
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