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192883-12-8

192883-12-8 Structure

192883-12-8 Structure
IdentificationBack Directory
[Name]

N-3-Hydroxydecanoyl-L-hoMoserine Lactone
[CAS]

192883-12-8
[Synonyms]

N-3-Hydroxydecanoyl-L-hoMoserine Lactone
N-3-hydroxydecanoyl-L-Homoserine lactone (OH-C10-HSL)
3-Hydroxy-N-((S)-2-oxotetrahydrofuran-3-yl)decanamide
[Molecular Formula]

C14H25NO4
[MDL Number]

MFCD30187081
[MOL File]

192883-12-8.mol
[Molecular Weight]

271.35
Chemical PropertiesBack Directory
[Boiling point ]

516.8±50.0 °C(Predicted)
[density ]

1.09±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 20 mg/ml; DMSO: 20 mg/ml
[form ]

A crystalline solid
[pka]

14.25±0.20(Predicted)
Hazard InformationBack Directory
[Description]

N-3-hydroxydecanoyl-L-Homoserine lactone is a bacterial quorum-sensing molecule that has been found in B. pseudomallei. It induces expression of tda, a gene with roles in the production of the antibiotic tropodithietic acid (TDA; ) and the algicide roseobacticide, in P. inhibens.
[Uses]

N-3-hydroxydecanoyl-L-homoserine Lactone is a small signaling molecule that is secreted by different types of gram-negative bacteria as a autoinducer. N-3-hydroxydecanoyl-L-homoserine Lactone has been used in studies involving interspecies signaling through QscR, a quorum receptor of pseudomonas aeruginosa.
[References]

[1] RURUN WANG M S étienne Gallant. Investigation of the Genetics and Biochemistry of Roseobacticide Production in the Roseobacter Clade Bacterium Phaeobacter inhibens[J]. mBio, 2016, 7 1. DOI: 10.1128/mbio.02118-15
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