| Identification | Back Directory | [Name]
2H-Pyran-4-acetamide, tetrahydro-N-hydroxy-4-[(4-phenoxyphenyl)sulfonyl]- | [CAS]
193022-38-7 | [Synonyms]
RS 104966
RS-104966
2H-Pyran-4-acetamide, tetrahydro-N-hydroxy-4-[(4-phenoxyphenyl)sulfonyl]- | [Molecular Formula]
C19H21NO6S | [MOL File]
193022-38-7.mol | [Molecular Weight]
391.44 |
| Hazard Information | Back Directory | [Description]
RS-104966 is a collagenase inhibitor. It acts by inducing the conformational change in the side-chains of the S1 pocket of MMP-1. | [Uses]
RS-104966 is a potent collagenase-1 (MMP-1) inhibitor. RS-104966 induces a conformational change in the side chains of the S10 pocket of MMP-1[1]. | [IC 50]
collagenases 1 | [References]
[1] K?llblad P, et al. Efficient conformational sampling of local side-chain flexibility. J Mol Biol. 2003 Mar 7;326(5):1651-65. DOI:10.1016/s0022-2836(03)00083-4 |
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