ChemicalBook--->CAS DataBase List--->1932791-56-4

1932791-56-4

Request For Quotation

Directory

Chemical Properties

Hazard Information

1932791-56-4 Structure

1932791-56-4 Structure

Identification	Back Directory
[Name] Monomethyl auristatin E intermediate-14
[CAS] 1932791-56-4
[Synonyms] Monomethyl auristatin E intermediate-14
[Molecular Formula] C13H19NO2
[MOL File] 1932791-56-4.mol
[Molecular Weight] 221.3

Chemical Properties	Back Directory
[Boiling point ] 349.787±25.00 °C(Press: 760.00 Torr)(predicted)
[density ] 1.059±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[form ] Solid
[pka] 2.427±0.24(predicted)
[color ] White to off-white

Hazard Information	Back Directory
[Uses] Monomethyl auristatin E intermediate-14 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
[References] [1] Lisa Buckel, et al. Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery. Cancer Res. 2015 Apr 1;75(7):1376-87. DOI:10.1158/0008-5472.CAN-14-1931

1932791-56-4 suppliers list

Company Name:	Shanghai Haohong Pharmaceutical Co., Ltd.
Tel:	400-8210725 4008210725
Website:	https://www.leyan.com/

Tags:1932791-56-4 Related Product Information

13139-16-7 138775-22-1 143688-83-9 1509-34-8 1509-35-9 319-78-8