| Identification | Back Directory | [Name]
1H-Pyrazole-4-carboxamide, N-[(3-fluoro-4-methoxy-2-pyridinyl)methyl]-3-(methoxymethyl)-1-[[4-[(2-oxo-1(2H)-pyridinyl)methyl]phenyl]methyl]- | [CAS]
1933514-13-6 | [Synonyms]
KVD-900
Sebetralstat
KVD900/
Sebetralstat
N-((3-fluoro-4-methoxypyridin-2-yl)methyl)-3-(methoxymethyl)-1-(4-((2-oxopyridin-1(2H)-yl)methyl)benzyl)-1H-pyrazole-4-carboxamide
1H-Pyrazole-4-carboxamide, N-[(3-fluoro-4-methoxy-2-pyridinyl)methyl]-3-(methoxymethyl)-1-[[4-[(2-oxo-1(2H)-pyridinyl)methyl]phenyl]methyl]- | [Molecular Formula]
C26H26FN5O4 | [MOL File]
1933514-13-6.mol | [Molecular Weight]
491.51 |
| Chemical Properties | Back Directory | [Boiling point ]
762.3±60.0 °C(Predicted) | [density ]
1.29±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : ≥ 125 mg/mL (254.32 mM) | [form ]
Solid | [pka]
12.49±0.46(Predicted) | [color ]
White to off-white | [InChIKey]
KGMPDQIYDKKXRD-UHFFFAOYSA-N | [SMILES]
N1(CC2=CC=C(CN3C(=O)C=CC=C3)C=C2)C=C(C(NCC2=NC=CC(OC)=C2F)=O)C(COC)=N1 |
| Hazard Information | Back Directory | [Uses]
Sebetralstat (KVD900) is a plasma kallikrein inhibitor (WO2016083820). Sebetralstat can be used for the research of metabolic diseases[1]. | [References]
[1] WO2016083820 |
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