| Identification | Back Directory | [Name]
4,5-DIHYDRO-2-(ETHOXYCARBONYL)NAPTHO(1,2-B)THIOPENE | [CAS]
19397-74-1 | [Synonyms]
4,5-DIHYDRO-2-(ETHOXYCARBONYL)NAPTHO(1,2-B)THIOPENE
4,5-dihydro-2-(ethoxycarbonyl)naphtho[1,2-b]thiophene
Naphtho[1,2-b]thiophene-2-carboxylic acid, 4,5-dihydro-, ethyl ester | [Molecular Formula]
C15H14O2S | [MDL Number]
MFCD00022192 | [MOL File]
19397-74-1.mol | [Molecular Weight]
258.34 |
| Chemical Properties | Back Directory | [Melting point ]
82-83 °C(Solv: ethanol (64-17-5)) | [Boiling point ]
417.7±33.0 °C(Predicted) | [density ]
1.230±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature |
| Hazard Information | Back Directory | [Synthesis]
Ethyl acetate (0.94 g, 7.8 mmol) was slowly added to a solution of sodium ethoxide (1.1 g, 15.6 mmol) in anhydrous ethanol (8 mL) at 0 °C. Subsequently, 1-chloro-3,4-dihydronaphthalene-2-carbaldehyde (1.5 g, 7.8 mmol) was added dropwise to the above reaction mixture and the reaction system was stirred at room temperature overnight. After completion of the reaction, the mixture was refluxed for half an hour and then poured into pre-cooled brine and extracted with ethyl acetate (3 x 60 mL). The organic phases were combined, washed with saturated brine (2 x 50 mL) and dried over anhydrous sodium sulfate. After concentration under reduced pressure, the crude product was purified by recrystallization from ethanol to give 1.3 g of the yellow solid product ethyl 4,5-dihydronaphtho[1,2-b]thiophene-2-carboxylate in 66.3% yield. | [References]
[1] Patent: CN108727416, 2018, A. Location in patent: Paragraph 0335; 0336; 0337 |
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| Company Name: |
Energy Chemical
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| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
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