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194034-59-8

194034-59-8 Structure

194034-59-8 Structure
IdentificationBack Directory
[Name]

2-AMino-6-chloropurine-9-(2'-O-Methyl)riboside
[CAS]

194034-59-8
[Synonyms]

2-AMino-6-chloropurine-9-(2'-O-Methyl)riboside
9H-Purin-2-amine, 6-chloro-9-(2-O-methyl-β-D-ribofuranosyl)-
6-chloro-9-(2-O-Methyl-beta-D-ribofuranosyl)-9H-purin-2-aMine
2-AMino-6-chloro-9-(2'-O -Methyl-beta-D-ribofuranosyl)-9H-purine
(2R,3R,4R,5R)-5-(2-Amino-6-chloro-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol
[Molecular Formula]

C11H14ClN5O4
[MOL File]

194034-59-8.mol
[Molecular Weight]

315.71
Chemical PropertiesBack Directory
[Boiling point ]

675.6±65.0 °C(Predicted)
[density ]

1.94±0.1 g/cm3(Predicted)
[pka]

13.09±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

6-Chloro-9-(2-O-methyl-beta-D-ribofuranosyl)-9H-purin-2-amine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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