| Identification | Back Directory | [Name]
4-Benzyloxy-3-methyl-phenol | [CAS]
194157-10-3 | [Synonyms]
4-Benzyloxy-3-methyl-phenol
7-oxa-2-azaspiro[3.5]nona...
7-oxa-2-azaspiro[3.5]nonane (HCl)
7-Oxa-2-azaspiro[3.5]nonane (9CI)
7-Oxa-2-azaspiro[3.5]nonane HCl salt
7-oxa-2-azaspiro[3.5]nonane - X12040
7-Oxa-2-aza-spiro[3.5]nonane oxalate forM
7-oxa-2-azaspiro[3.5]nonane oxalic acid salt | [Molecular Formula]
C7H13NO | [MDL Number]
MFCD11204146 | [MOL File]
194157-10-3.mol | [Molecular Weight]
127.18 |
| Chemical Properties | Back Directory | [Boiling point ]
208.4±40.0 °C(Predicted) | [density ]
1.04±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [pka]
10.49±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
7-Oxa-2-azaspiro[3.5]nonane is used in preparation of the zeste enhancer homolog 2 inhibitor and their medical applications. | [Synthesis]
The synthesis of 7-oxa-2-azaspiro[3.5]nonane is as follows: (1) under the condition of an acid binding agent, carrying out a first cyclization reaction on the compound 1 and the compound 2 in N, N-dimethylformamide under the action of a phase transfer catalyst and iodo metal salt to obtain a compound 3;(2) Carrying out a second cyclization reaction on the compound 3, lithium aluminum hydride and a reaction solvent to obtain the product.
![7-oxa-2-azaspiro[3.5]nonane synthesis route](/NewsImg/2025-12-18/6390166480868558284203919.png "7-oxa-2-azaspiro[3.5]nonane synthesis route")
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