| Identification | Back Directory | [Name]
FUMARIC ACID-D4 | [CAS]
194160-45-7 | [Synonyms]
FUMARIC ACID-D4
fumaric-D2 acid-D2
FUMARIC-D2 ACID-D2, 98 ATOM % D | [Molecular Formula]
C4H4O4 | [MDL Number]
MFCD00190450 | [MOL File]
194160-45-7.mol | [Molecular Weight]
116.07 |
| Chemical Properties | Back Directory | [Melting point ]
299-300 °C (subl.)(lit.) | [form ]
solid | [InChI]
1S/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8)/b2-1+/i1D,2D/hD2 | [InChIKey]
VZCYOOQTPOCHFL-JXRVJRKUSA-N | [SMILES]
[2H]OC(=O)\C([2H])=C(/[2H])C(=O)O[2H] | [CAS Number Unlabeled]
110-17-8 |
| Hazard Information | Back Directory | [Uses]
Fumaric acid-d4 is the deuterium labeled Fumaric acid[1]. Fumaric acid, associated with fumarase deficiency, is identified as an oncometabolite or an endogenous, cancer causing metabolite[2]. | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Whelan DT, et al. Fumaric aciduria: a new organic aciduria, associated with mental retardation and speech impairment. Clin Chim Acta. 1983 Aug 31;132(3):301-8. DOI:10.1016/0009-8981(83)90008-6 |
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