| Identification | Back Directory | [Name]
Oleana-1,12-dien-28-oic acid, 2-hydroxy-3-oxo- | [CAS]
194235-21-7 | [Synonyms]
Pancreatic lipase/Carboxylesterase 1-IN-1
Oleana-1,12-dien-28-oic acid, 2-hydroxy-3-oxo- | [Molecular Formula]
C30H44O4 | [MOL File]
194235-21-7.mol | [Molecular Weight]
468.67 |
| Chemical Properties | Back Directory | [Boiling point ]
593.3±50.0 °C(Predicted) | [density ]
1.15±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
4.63±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Pancreatic lipase/Carboxylesterase 1-IN-1 (Compound 39) is a potent dual inhibitor of pancreatic lipase (PL) and human carboxylesterase 1A (hCES1A) with IC50 values of 2.13?μM and 0.055? μM against PL and hCES1A[1]. | [References]
[1] Zhang J, et al. Discovery of triterpenoids as potent dual inhibitors of pancreatic lipase and human carboxylesterase 1. J Enzyme Inhib Med Chem. 2022 Dec;37(1):629-640. DOI:10.1080/14756366.2022.2029855 |
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