| Identification | Back Directory | [Name]
LYS-LYS-LYS-LYS-LYS | [CAS]
19431-21-1 | [Synonyms]
Lys5
pentalysine
LYS-LYS-LYS-LYS-LYS
5-mer polyLys PO00002137-02
Lys-Lys-Lys-Lys-Lys >=55% peptide basis
L-Lysyl-L-lysyl-L-lysyl-L-lysyl-L-lysine
L-Lysine,L-lysyl-L-lysyl-L-lysyl-L-lysyl- | [Molecular Formula]
C30H62N10O6 | [MDL Number]
MFCD00083765 | [MOL File]
19431-21-1.mol | [Molecular Weight]
658.88 |
| Chemical Properties | Back Directory | [Boiling point ]
1037.5±65.0 °C(Predicted) | [density ]
1.163±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
powder | [pka]
3.27±0.10(Predicted) | [color ]
white | [Sequence]
Lys-Lys-Lys-Lys-Lys |
| Hazard Information | Back Directory | [Uses]
Penta lysine is an antibacterial agent, that inhibits E. coli, A. baumannii, P. aeruginos, S. aureus, and B. subtilis, with MIC of 1.1-18 μM[1]. | [Biochem/physiol Actions]
Short poly-L-lysines polypeptides such as trilysine (lys3), tetralysine (tetra-L-lysine, lys4) and pentalysine (penta-L-lysine, lys5) are cationic moieties that may be used in the construction of gene delivery vectors and DNA nanoparticles. | [References]
[1] Albada HB, et al., Short antibacterial peptides with significantly reduced hemolytic activity can be identified by a systematic L-to-D exchange scan of their amino acid residues. ACS Comb Sci. 2013 Nov 11;15(11):585-92. DOI:10.1021/co400072q |
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YantaiBio
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Fuan Bio
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