| Identification | Back Directory | [Name]
7-BROMO-1H-QUINAZOLIN-4-ONE | [CAS]
194851-16-6 | [Synonyms]
7-bromoquinazoL
7-Bromo-4-quinazolone
7-BroMoquinazolin-4-one
7-Bromo-3H-quizolin-4-one
7-Bromo-3H-quinazolin-4-one
7-BROMOQUINAZOLIN-4(3H)-ONE
7-BroMoquinazolin-4(1H)-one
7-BROMO-1H-QUINAZOLIN-4-ONE
7-BroMo-3,4-dihydroquinaz...
4(1H)-Quinazolinone, 7-bromo-
4(3H)-Quinazolinone, 7-bromo-
7-bromo-4(3H)-Quinazolinone 97%
7-BROMO-3,4-DIHYDROQUINAZOLIN-4-ONE
7-BroMo-3,4-dihydroquinazolin-4-one, 95+% | [Molecular Formula]
C8H5BrN2O | [MDL Number]
MFCD06659945 | [MOL File]
194851-16-6.mol | [Molecular Weight]
225.04 |
| Chemical Properties | Back Directory | [Boiling point ]
350.1±44.0 °C(Predicted) | [density ]
1.82±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
0.36±0.20(Predicted) | [Appearance]
White to off-white Solid |
| Questions And Answer | Back Directory | [Application]
7-Bromo-3,4-dihydroquinazolin-4-one is a quinazolone compound. Quinazolones are a class of nitrogen-containing heterocyclic compounds with good biomedical activity, due to their broad range of biological and pharmaceutical activities. |
| Hazard Information | Back Directory | [Synthesis]
General procedure for the synthesis of 7-bromo-3,4-dihydroquinazolin-4-one from 2-amino-4-bromobenzoic acid and compound (CAS: 77287-34-4): 0.0 g (1.56 mol) of 2-amino-4-bromobenzoic acid was suspended in 970 mL of formamide, followed by stirring of the reaction for 12 hours at 170°C. Upon completion of the reaction, a conventional post-processing was carried out to give 326.0 g of 7-bromo-3H-quinazolin-4-one; which was analyzed by HPLC/MS as a solid product with (M + H)+ = 226. | [References]
[1] Patent: US2013/12489, 2013, A1. Location in patent: Paragraph 0182
[2] Patent: WO2010/146173, 2010, A1. Location in patent: Page/Page column 16
[3] Patent: CN105503744, 2016, A. Location in patent: Paragraph 0033; 0036; 0037
[4] Journal of Organic Chemistry, 1952, vol. 17, p. 149,153
[5] Patent: US2016/31860, 2016, A1. Location in patent: Paragraph 0110; 0111 |
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