| Identification | Back Directory | [Name]
8-HYDROXY-7-METHOXYCOUMARIN | [CAS]
19492-03-6 | [Synonyms]
DAPHNETIN METHYL ETHER
Daphnetin 7-Methyl ethe
DAPHNETIN-7-METHYL ETHER
8-HYDROXY-7-METHOXYCOUMARIN
7-Methoxy-8-hydroxycoumarin
8-hydroxy-7-methoxychromen-2-one
8-Hydroxy-7-methoxy-2H-chromen-2-one
7-Methoxy-8-hydroxy-2H-1-benzopyran-2-one
8-Hydroxy-7-methoxy-2H-1-benzopyran-2-one
2H-1-Benzopyran-2-one, 8-hydroxy-7-methoxy-
8-HYDROXY-7-METHOXYCOUMARIN ISO 9001：2015 REACH | [EINECS(EC#)]
218-290-4 | [Molecular Formula]
C10H8O4 | [MDL Number]
MFCD00075652 | [MOL File]
19492-03-6.mol | [Molecular Weight]
192.17 |
| Hazard Information | Back Directory | [Uses]
8-Hydroxy-7-methoxycoumarin is a phenylpropanoid isolated from the calyxes of Physalis alkekengi L. var. franchetii (Mast.) Makino. 8-Hydroxy-7-methoxycoumarin shows cytotoxicity against GLC4 and COLO 320 cancer cell after continuous incubation (4 days) with IC50s of 179 μM and 145 μM[1][2]. | [Definition]
ChEBI: 8-Hydroxy-7-methoxy-2H-1-benzopyran-2-one is a hydroxycoumarin. | [Synthesis]
Preparation of 8-HYDROXY-7-METHOXYCOUMARIN (ryanodine-7-methyl ether) (Ⅱ-aa): weighing 7,8-dihydroxycoumarin 500mg in a three-mouth bottle, adding N,N-dimethylformamide 5mL to dissolve the sample, adding sodium carbonate 850mg, stirring the reaction for 1 | [References]
[1] HuiLv, et al. Chemical constituents from the calyxes of Physalis alkekengi L. var. franchetii (Mast.) Makino. Biochemical Systematics and Ecology, Volume 78, June 2018, Pages 63-65.
[2] H Kolodzie, et al. Structure-cytotoxicity relationships of a series of natural and semi-synthetic simple coumarins as assessed in two human tumour cell lines. Z Naturforsch C J Biosci. 1997 Mar-Apr;52(3-4):240-4. DOI:10.1515/znc-1997-3-416 |
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Alfa Aesar
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400-6106006 |
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http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
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400-0056266 |
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www.energy-chemical.com |
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