| Identification | Back Directory | [Name]
AS-601811 | [CAS]
194979-95-8 | [Synonyms]
AS-601811
UNII-LIV8A6AE5F
AS601811|||AS 601811|||UNII-LIV8A6AE5F
3H-Benzo[c]quinolizin-3-one, 1,2,5,6-tetrahydro-4,8-dimethyl- | [Molecular Formula]
C15H17NO | [MOL File]
194979-95-8.mol | [Molecular Weight]
227.3 |
| Hazard Information | Back Directory | [Uses]
AS-601811(compound 47) is a 5alpha-reductase 1 inhibitor with the IC50 of 20 nM and can be used for study of alopecia and hirsutism[1]. | [References]
[1] Occhiato EG, et al. Synthesis, biological activity, and three-dimensional quantitative structure-activity relationship model for a series of benzo[c]quinolizin-3-ones, nonsteroidal inhibitors of human steroid 5alpha-reductase 1. J Med Chem. 2004;47(14):3546-3560. DOI:10.1021/jm031131o |
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