| Identification | Back Directory | [Name]
1951424-89-7 | [CAS]
1951424-89-7 | [Synonyms]
CAS_1951424-89-7
Desthiobiotin-PEG4-propargyl
4-Imidazolidinehexanamide, 5-methyl-2-oxo-N-3,6,9,12-tetraoxapentadec-14-yn-1-yl-, (4R,5S)- | [Molecular Formula]
C21H37N3O6 | [MOL File]
1951424-89-7.mol | [Molecular Weight]
427.54 |
| Hazard Information | Back Directory | [Uses]
Desthiobiotin-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Desthiobiotin-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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