| Identification | Back Directory | [Name]
MTX-211 | [CAS]
1952236-05-3 | [Synonyms]
MTX-211
CPD1541
MTX-211, >98%
MTX-211; MTX211; MTX 211;1952236-05-3
N-(2-chloro-5-(4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl)pyridin-3-yl)methanesulfonamide
Methanesulfonamide, N-[2-chloro-5-[4-[(3-chloro-4-fluorophenyl)amino]-6-quinazolinyl]-3-pyridinyl]- | [Molecular Formula]
C20H14Cl2FN5O2S | [MDL Number]
MFCD31620832 | [MOL File]
1952236-05-3.mol | [Molecular Weight]
478.33 |
| Chemical Properties | Back Directory | [Boiling point ]
642.8±65.0 °C(Predicted) | [density ]
1.577±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : ≥ 100 mg/mL (209.06 mM) | [form ]
Solid | [pka]
5.61±0.50(Predicted) | [color ]
Light yellow to khaki |
| Hazard Information | Back Directory | [Uses]
MTX-211 (Mol 211) is a dual inhibitor of EGFR and PI3K with IC50 values of ＜100 nM. MTX-211 can be used for the research of cancer and other diseases[1]. | [IC 50]
EGFR; PI3K | [References]
[1] Small molecule inhibitors of egfr and pi3k. WO 2016100347 A2 |
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