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195611-82-6

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195611-82-6 Structure

195611-82-6 Structure
IdentificationBack Directory
[Name]

GW7604
[CAS]

195611-82-6
[Synonyms]

GW7604
2-Propenoic acid, 3-[4-[(1E)-1-(4-hydroxyphenyl)-2-phenyl-1-buten-1-yl]phenyl]-, (2E)-
[Molecular Formula]

C25H22O3
[MDL Number]

MFCD29770803
[MOL File]

195611-82-6.mol
[Molecular Weight]

370.44
Chemical PropertiesBack Directory
[Boiling point ]

543.8±38.0 °C(Predicted)
[density ]

1.196±0.06 g/cm3(Predicted)
[pka]

4.55±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

(E)-GW7604 is the (E)-isomer of GW7604, an antiestrogen and a metabolite of GW5638 (HY-112746), which is a high-affinity estrogen receptor (ER) antagonist[1].
[References]

[1] Willson TM, et al. Dissection of the molecular mechanism of action of GW5638, a novel estrogen receptor ligand, provides insights into the role of estrogen receptor in bone. Endocrinology. 1997 Sep;138(9):3901-11. DOI:10.1210/endo.138.9.5358
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