| Identification | Back Directory | [Name]
(3β,7β,12β,20Z )- 3,7,12- trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid | [CAS]
1961358-02-0 | [Synonyms]
(3β,7β,12β,20Z )- 3,7,12- trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid
(3β,7β,12β,20Z )- 3,7,12- trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid
Lanosta-8,20(22)-dien-26-oic acid, 3,7,12-trihydroxy-11,15,23-trioxo-, (3β,7β,12β,20Z)-
(3beta,7beta,12beta,20Z)- 3,7,12- trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid | [Molecular Formula]
C30H42O8 | [MDL Number]
MFCD31747149 | [MOL File]
1961358-02-0.mol | [Molecular Weight]
530.66 |
| Chemical Properties | Back Directory | [Boiling point ]
737.2±60.0 °C(Predicted) | [density ]
1.28±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
4.57±0.23(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
(3β,7β,12β,20Z)-3,7,12-Trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid, a lanostane triterpenoids, exhibits obvious NO inhibitory activity on n LPS-induced BV-2 microglia cells with an IC50 of 9.55 uM. (3β,7β,12β,20Z)-3,7,12-Trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid has anti-inflammatory activities[1]. | [References]
[1] Yang Jiao, et al. Lanostane triterpenoids from Ganoderma curtisii and their NO production inhibitory activities of LPS-induced microglia. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3556-61. DOI:10.1016/j.bmcl.2016.06.023 |
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