1965-54-4

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1965-54-4 Structure

Identification	Back Directory
[Name] 2-[(4-NITROPHENYL)AMINO]ETHANOL
[CAS] 1965-54-4
[Synonyms] TIMTEC-BB SBB006779 2-(4-nitroanilino)ethanol 2-[(4-NITROPHENYL)AMINO]ETHANOL Ethanol, 2-[(4-nitrophenyl)amino]-
[Molecular Formula] C8H10N2O3
[MDL Number] MFCD00156330
[MOL File] 1965-54-4.mol
[Molecular Weight] 182.18

Safety Data	Back Directory
[Symbol(GHS) ] GHS06
[Signal word ] Danger
[Hazard statements ] H302-H317-H311+H331-H315
[Precautionary statements ] P280-P361+P364-P362+P364

Hazard Information	Back Directory
[Uses] 2-[(4-nitrophenyl)amino]ethanol is used to prepare phenylpurinediamine derivatives as a class of reversible kinase inhibitors targeting both EGFR-activating and resistance mutations of lung cancer. It is also used to synthesize benzannulated N-heterocycles via palladium-catalyzed domino intermolecular alkylation/intramolecular amination of functionalized aryl iodides and bromoalkylamines.
[Synthesis Reference(s)] Synthesis, p. 606, 1976 DOI: 10.1055/s-1976-24135

Spectrum Detail	Back Directory
[Spectrum Detail] 2-[(4-NITROPHENYL)AMINO]ETHANOL(1965-54-4)MS 2-[(4-NITROPHENYL)AMINO]ETHANOL(1965-54-4)IR1 2-[(4-NITROPHENYL)AMINO]ETHANOL(1965-54-4)IR2

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