| Identification | Back Directory | [Name]
8-Oxocoptisine | [CAS]
19716-61-1 | [Synonyms]
8-Oxycoptisine
8-Oxocoptisine
4H-Bis[1,3]benzodioxolo[5,6-a:4',5'-g]quinolizin-4-one, 6,7-dihydro- | [Molecular Formula]
C19H13NO5 | [MDL Number]
MFCD03792766 | [MOL File]
19716-61-1.mol | [Molecular Weight]
335.31 |
| Chemical Properties | Back Directory | [Melting point ]
283-285℃ | [Boiling point ]
617.5±55.0 °C(Predicted) | [density ]
1.61±0.1 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
-20°C | [solubility ]
Chloroform: soluble | [form ]
Cryst. | [pka]
-1.62±0.20(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the root of Thalictrum glandulosissimum. | [Uses]
8-Oxocoptisine is a natural protoberberine alkaloid with anti-cancer activity[1]. | [Safety Profile]
A poison by ingestion.When heated to decomposition it emits toxic vapors of NOx. | [storage]
-20°C | [References]
[1] Ping Qian, et al. Five new alkaloids from Coptidis Rhizoma-Euodiae Fructus couple and their cytotoxic activities against gastrointestinal cancer cells. Fitoterapia. 2014 Mar;93:74-80. DOI:10.1016/j.fitote.2013.12.016 |
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