| Identification | Back Directory | [Name]
AC-ALA-THR-LEU-ASP-ALA-LEU-LEU-ALA-ALA-LEU-ARG-ARG-ILE-GLN-NH2 | [CAS]
197230-90-3 | [Synonyms]
NTR 368
M.W. 1565.86 C69H124N22O19
Neurotrophin receptor (368-381) amide
Acetyl-Neurotrophin Receptor (368-381) amide
AC-NEUROTROPHIN RECEPTOR (368-381) AMIDE (HUMAN)
ACETYL-NEUROTROPHIN RECEPTOR (365-378) AMIDE (RAT)
ACETYL-NEUROTROPHIN RECEPTOR (368-381) AMIDE (HUMAN)
AC-ALA-THR-LEU-ASP-ALA-LEU-LEU-ALA-ALA-LEU-ARG-ARG-ILE-GLN-NH2
AC-ALA-THR-LEU-ASP-ALA-LEU-LEU-ALA-ALA-LEU-ARG-ARG-LEU-GLN-NH2
Acetyl-Neurotrophin Receptor (368-381) amide (human) Ac-Ala-Thr-Leu-Asp-Ala-Leu-Leu-Ala-Ala-Leu-Arg-Arg-Ile-Gln-NH2
L-Glutamamide, N-acetyl-L-alanyl-L-threonyl-L-leucyl-L-α-aspartyl-L-alanyl-L-leucyl-L-leucyl-L-alanyl-L-alanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl- (9CI) | [Molecular Formula]
C69H124N22O19 | [MDL Number]
MFCD02261951 | [MOL File]
197230-90-3.mol | [Molecular Weight]
1565.86 |
| Chemical Properties | Back Directory | [density ]
1.391±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [storage temp. ]
-15°C
| [form ]
Powder | [pka]
4.197±0.10(predicted) | [Water Solubility ]
Soluble to 1 mg/ml in water |
| Hazard Information | Back Directory | [Uses]
NTR 368 is a peptide derived from p75 neurotrophin receptor (p75NTR) corresponding to residues 368-381 of the human receptor. NTR 368 has helix forming propensity in the presence of micellar lipid. NTR 368 is a potent inducer of neural apoptosis[1]. | [References]
[1] M R Hileman, et al. A cytoplasmic peptide of the neurotrophin receptor p75NTR: induction of apoptosis and NMR determined helical conformation. FEBS Lett. 1997 Sep 29;415(2):145-54. DOI:10.1016/s0014-5793(97)01113-7 |
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