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197917-10-5

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197917-10-5 Structure

197917-10-5 Structure
IdentificationBack Directory
[Name]

CK 119
[CAS]

197917-10-5
[Synonyms]

CK 119
GC-6119
UNII-AL53N923EI
Pyridazino[4,5-c]pyridazine-3,4-dicarboxylic acid, 6-[(4-chlorophenyl)methyl]-1,4,5,6-tetrahydro-1,4-dimethyl-5-oxo-, 3,4-diethyl ester
[Molecular Formula]

C21H23ClN4O5
[MOL File]

197917-10-5.mol
[Molecular Weight]

446.88
Chemical PropertiesBack Directory
[Boiling point ]

551.7±60.0 °C(Predicted)
[density ]

1.34±0.1 g/cm3(Predicted)
[pka]

1.19±0.60(Predicted)
Hazard InformationBack Directory
[Uses]

CK-119 is a potent interleukin-1 blocker. CK-119 inhibits the cell growth of fibroblast-like corneal and conjunctival cells, mainly by inhibiting DNA and RNA syntheses[1].
[IC 50]

IL-1
[References]

[1] Bo X, et al. Inhibition of fibroblast-like cell proliferation by interleukin-1 blockers, CK-119 and CK-122. Zhongguo Yao Li Xue Bao. 1998 Jul;19(4):304-8. PMID:10375772
197917-10-5 suppliers list
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Company Name: BOC Sciences  
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Company Name: TargetMol Chemicals Inc.  
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Website: https://www.targetmol.cn/
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