| Identification | Back Directory | [Name]
ABT-594 | [CAS]
198283-73-7 | [Synonyms]
ABT-59
CS-2417
ABT-594
Ebanicline
198283-73-7
Tebanicline
ABT594;ABT 594
ABT 594,Tebanicline
Tebanicline(ABT-594)
(R)-5-(azetidin-2-ylmethoxy)-2-chloropyridine
5-[[(2R)-azetidin-2-yl]methoxy]-2-chloropyridine
Pyridine, 5-[(2R)-2-azetidinylmethoxy]-2-chloro- | [Molecular Formula]
C9H11ClN2O | [MOL File]
198283-73-7.mol | [Molecular Weight]
198.652 |
| Chemical Properties | Back Directory | [Melting point ]
116-117 °C | [Boiling point ]
321.1±22.0 °C(Predicted) | [density ]
1.228±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
H2O: 2 mg/mL, clear | [form ]
powder | [pka]
10.05±0.40(Predicted) | [color ]
white to beige | [Water Solubility ]
H2O: 2mg/mL, clear | [InChI]
1S/C9H11ClN2O/c10-9-2-1-8(5-12-9)13-6-7-3-4-11-7/h1-2,5,7,11H,3-4,6H2/t7-/m1/s1 | [InChIKey]
MKTAGSRKQIGEBH-SSDOTTSWSA-N | [SMILES]
Clc1ncc(cc1)OC[C@@H]2NCC2 |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H336 | [Precautionary statements ]
P261-P271-P304+P340+P312-P403+P233-P405-P501 | [WGK Germany ]
WGK 3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
STOT SE 3 | [Toxicity]
mouse,LD50,intraperitoneal,3794ug/kg (3.794mg/kg),BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD,European Journal of Pharmacology. Vol. 346, Pg. 23, 1998. |
| Hazard Information | Back Directory | [Uses]
Analgesic (cholinergic channel modulator). | [Biological Activity]
Tebanicline (ABT-594) is a partial agonist at neural nicotinic acetylcholine receptorsbinding to both the α3β4 and the α4β2 subtypes. It is a less toxic analog of epibatidine with potent antinociceptive effects. |
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| Company Name: |
Twochem Co.Ltd.
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| Tel: |
021-58111628 15800915896 |
| Website: |
cn.twochem.com |
| Company Name: |
BOC Sciences
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| Tel: |
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| Website: |
https://www.bocsci.com |
| Company Name: |
Cckinase, Inc.
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| Tel: |
+1 (732)236-3202 |
| Website: |
www.cckinase.com |
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