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19877-89-5

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19877-89-5 Structure

19877-89-5 Structure
IdentificationBack Directory
[Name]

vincanol
[CAS]

19877-89-5
[Synonyms]

vincanol
Vincanolum
(3α,14α,16α)-14,15-Dihydroeburnamenin-14-ol
Eburnamenin-14-ol, 14,15-dihydro-, (3α,14β,16α)-
[EINECS(EC#)]

243-388-9
[Molecular Formula]

C19H24N2O
[MDL Number]

MFCD00868229
[MOL File]

19877-89-5.mol
[Molecular Weight]

296.412
Chemical PropertiesBack Directory
[Melting point ]

108-110 °C
[Boiling point ]

484.4±45.0 °C(Predicted)
[density ]

1.35±0.1 g/cm3(Predicted)
[pka]

14.30±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

Vincanol ((-)-Isoeburnamine) is a blocker of voltage-gated Na+ channels. Vincanol blocks Na+ currents with an IC50 value of 40 μM. Vincanol has neuroprotective effect[1].
[References]

[1] Erdo SA, et al. Vincamine and vincanol are potent blockers of voltage-gated Na+ channels. Eur J Pharmacol. 1996 Oct 24;314(1-2):69-73. DOI:10.1016/s0014-2999(96)00542-0
19877-89-5 suppliers list
Company Name: TargetMol Chemicals Inc.  
Telephone: 15002134094
Website: https://www.targetmol.cn/
Company Name: SHAANXI?DIDEU?MEDICHEM CO.LTD  
Telephone: 17691182729 17392216275
Website:
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