| Chemical Properties | Back Directory | [Boiling point ]
737.0±60.0 °C(Predicted) | [density ]
1.52±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
12.37±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Thiobis-β-Galactose-propyne is an effective multivalent galectin-3 (Gal-3) inhibitor. Galectin-3 is involved in many metabolism processes related to cancer. Galectin-3-IN-1 is a click chemistry reagent. It contains an alkyne group that can undergo a copper-catalyzed azide-alkyne cycloaddition (CuAAc) reaction with molecules that have an azide group[1]. | [IC 50]
Galectin-3 | [References]
[1] David Vrbata, et al. Glycopolymers Decorated with 3- O-Substituted Thiodigalactosides as Potent Multivalent Inhibitors of Galectin-3. J Med Chem. 2022 Mar 10;65(5):3866-3878. DOI:10.1021/acs.jmedchem.1c01625 |
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