| Identification | Back Directory | [Name]
ROCK2-IN-2 | [CAS]
1995065-79-6 | [Synonyms]
ROCK2-IN-2
1H-Indazol-5-amine, N-[5-[3-(2-oxazolyl)phenyl]-1,3,4-thiadiazol-2-yl]- | [Molecular Formula]
C18H12N6OS | [MDL Number]
MFCD31692339 | [MOL File]
1995065-79-6.mol | [Molecular Weight]
360.39 |
| Chemical Properties | Back Directory | [Boiling point ]
656.5±65.0 °C(Predicted) | [density ]
1.479±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
13.60±0.40(Predicted) | [color ]
Light yellow to green yellow |
| Hazard Information | Back Directory | [Uses]
ROCK2-IN-2 is a selective ROCK2 inhibitor extracted from patent US20180093978A1, Compound A-30, has an IC50 of <1 μM. | [IC 50]
ROCK2: 1 μM (IC50) | [References]
[1] Aicher, Thomas Daniel, et al. INDAZOLYL THIADIAZOLAMINES AND RELATED COMPOUNDS FOR INHIBITION OF RHO-ASSOCIATED PROTEIN KINASE AND THE TREATMENT OF DISEASE. US20180093978A1. |
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