| Identification | Back Directory | [Name]
NNC 26-9100 | [CAS]
199522-35-5 | [Synonyms]
NNC 26-9100
1-[3-[N-(5-Bromopyridin-2-yl)-N-(3,4-dichlorobenzyl)amino]propyl]-3-[3-(1H-imidazol-4-yl)propyl]thiourea
Thiourea, N-[3-[(5-bromo-2-pyridinyl)[(3,4-dichlorophenyl)methyl]amino]propyl]-N'-[3-(1H-imidazol-5-yl)propyl]- | [Molecular Formula]
C22H25BrCl2N6S | [MDL Number]
MFCD09038560 | [MOL File]
199522-35-5.mol | [Molecular Weight]
556.35 |
| Hazard Information | Back Directory | [Uses]
NNC 26-9100 is a Somatostatin (SRIF, somatotropin release inhibiting factor) receptor. | [Definition]
ChEBI: 1-[3-[(5-bromo-2-pyridinyl)-[(3,4-dichlorophenyl)methyl]amino]propyl]-3-[3-(1H-imidazol-5-yl)propyl]thiourea is an aminopyridine. | [Biological Activity]
Somatostatin sst 4 receptor agonist that displays > 100-fold selectivity over sst 2 receptors (K i values are 6 and 621 nM for sst 4 and sst 2 receptors respectively). Potently inhibits forskolin-induced cAMP accumulation (EC 50 = 26 nM). | [storage]
Store at -20°C |
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