| Identification | Back Directory | [Name]
4-(Pyrimidin-2-yl)benzoic acid | [CAS]
199678-12-1 | [Synonyms]
AKOS BAR-2339
4-(2-pyrimidinyl)benzoate
4-(PYRIMIDIN-2-YL)BENZOIC ACID
4-Pyrimidin-2-yl-benzoicacid95%
Benzoic acid, 4-(2-pyrimidinyl)-
Benzoic acid, 4-(2-pyrimidinyl)- (9CI)
4-(Pyrimidin-2-yl)benzoic acid MFCD01318668 | [Molecular Formula]
C11H8N2O2 | [MDL Number]
MFCD01318668 | [MOL File]
199678-12-1.mol | [Molecular Weight]
200.19 |
| Chemical Properties | Back Directory | [Melting point ]
238 °C | [Boiling point ]
301.5±34.0 °C(Predicted) | [density ]
1.302±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
3.67±0.10(Predicted) | [Appearance]
Off-white to light brown Solid |
| Hazard Information | Back Directory | [Uses]
4-Pyrimidin-2-yl-benzoic acid (cas# 199678-12-1) is a useful reactant for the synthesis of alkylimino-quinolinyl isoindolones. | [Synthesis]
In a 250 mL round bottom flask, the compound obtained in the previous step (4.4 g, 20.54 mmol, 1.00 eq.), sodium hydroxide (2.4 g, 60.00 mmol, 2.92 eq.), and methanol (50 mL) were mixed. The reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the pH of the reaction solution was adjusted to 7 with 1 M hydrochloric acid. the precipitated solid was collected by filtration to give 3.15 g of light yellow solid product in 77% yield. | [References]
[1] Patent: US2016/237043, 2016, A1. Location in patent: Paragraph 0553; 0555 |
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| Company Name: |
Heterochem
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| Telephone: |
027-88041443 13072715837 |
| Website: |
www.hetero-chem.com |
| Company Name: |
Cool Pharm, Ltd
|
| Telephone: |
021-60455363 18019463053 |
| Website: |
www.coolpharm.com |
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